
Momma's Meatloaf is a classic meatloaf that has the best flavor. This recipe is easy to make, holds together, and has the best glaze on top!
Preheat the oven to 350°F (175°C). Lightly grease a 9 x 13-inch baking dish with nonstick cooking spray.
In a large mixing bowl, combine 2 pounds ground beef, 1/2 cup diced white onion, 1 cup plain bread crumbs, 1/2 cup milk, 1 large egg, 2 tablespoons Worcestershire sauce, 1 teaspoon salt, 1 teaspoon dried basil, 1 teaspoon dried oregano, 1/2 teaspoon black pepper, and 1/2 teaspoon crushed red pepper flakes. Knead the mixture with clean hands until well combined. Do not overmix.
Shape the meat mixture into a loaf approximately 8 inches long, 4 inches wide, and 2 inches high, and place it centered in the prepared baking dish.
Bake for 45 minutes.
While the meatloaf is baking, prepare the glaze. In a small bowl, whisk together 1/2 cup ketchup, 2 tablespoons brown sugar, and 1 tablespoon Worcestershire sauce until smooth.
Remove meatloaf from oven and carefully brush the glaze over the top.
Increase the oven temperature to 400°F (205°C) and return the meatloaf to the oven. Bake for an additional 15 minutes, or until the internal temperature reaches 165°F (74°C) as measured with a food thermometer.
Let the meatloaf rest for 5 to 10 minutes before slicing. Serve hot.